Asinex is a leading chemical library and drug discovery services provider that specializes in creating highly novel scaffolds and associated fragments and compounds that allow the exploration of previously untouched areas of bioactive chemical space.
ASINEX (founded in 1994) has a total of 550,000 compounds. However, size isn't everything, of more importance is the 1500 novel in-house designed lead-like scaffolds, 80% of which have no references in literature. ASINEX has an impressive collection of 45,000 fragments and building blocks (less than 300MW), of which 8,000 are novel. Additionally, targeted libraries are available for kinases, GPCRs, ion channels, proteases, protein-protein interactions and anti-bacterial / anti-infectious targets.
The BioDesign libraries are ASINEX's latest innovation. This represents a synergic compromise between incorporating natural product privileged features and allowing straightforward screening and follow up chemistry. At the heart of the BioDesign concept is the incorporation of saturated, spiro and oxy features along with chirality, 3D geometry and good experimental solubility. ASINEX is focusing on compounds which are highly privileged and at the same time under-represented in commercial sources.
ASINEX's Libraries (http://www.asinex.com/Libraries.html)
ASINEX's Services (http://www.asinex.com/services.html)
Platinum Collection
The Platinum Collection is a proven source of 'hit' compounds.
Designed in their own computational department, and synthesized in their own labs. Around 120,000 compounds make this one of the largest in-house collections available. Asinex are sure that you will find this collection to be an interesting and unique source of diversity. These templates are unique to ASINEX, you won't find them in other collections.
- 117,7684 novel hand-crafted compounds, all available from the shelf
- Created from 8500 Building Blocks, of which over 5000 are unique to ASINEX
- 87% of compounds with 3-4 points of diversity
- Min.Purity 90% (Avg.95%)
- Protocols of synthesis are available for all compounds
- Lead optimization can be provided for all compounds (10% discount on FTE rate)
- ADME & Tox properties are predicted (calculated &/or measured)
- NMR spectra as TIFF or WinNMR files for all compounds
Delivery info
Delivery time 1-2 weeks
Available amount is 0.1 - 250mg
100% delivery of refill requests in 1 week
Supplied in customer's or ASINEX's vials (96 well plates, micronic tubes, glass vials, etc.).
Supplied as dry powder, dry film & in DMSO solution.
ASINEX or the customers labels can be used.
Cherry picking available
Gold Collection
The original ASINEX product, dating from 1994. It is composed of compounds acquired from contract chemists.
This collection is designed with maximum attention to drug-likeness. This historical collection has ADMET,
and solubility prediction, plus 16 other bio-physical properties.
Some in-house designed compounds have been included in the collection in order to improve the efficiency of the collection. These compounds have similar chemo-types to those already in this collection. The 2 main compound collections are based on different chemo-types, and are alternative sources of diversity.
- 208,958 novel hand-crafted compounds
- Covers 85% of the chemical space of all historical collections
- 40,000 compounds collected during 1994-1997 and rechecked in 2000
- 30,000 in-house synthesized compounds
- Minimum purity 90% (Avg 95%)
- NMR spectra as TIFF or WinNMR files for all compounds
- Lead Optimisation and protocols can be provided for a high percentage of compounds
Delivery info
Delivery time 1-2 weeks
Available amount is 0.1 - 250mg
95% delivery of refill requests (1-5mg), 90% (10mg), 80% (20mg) in 1-3 weeks
Supplied in customer's or ASINEX's vials (96 well plates, micronic tubes, glass vials, etc.)
Supplied as dry powder, dry film & in DMSO solution.
ASINEX or the customers labels can be used.
Cherry picking available.
Contact Details:-
20 Geroev Panfilovtzev Str. Bldg 1,
Moscow 125480,
Russia
Tel: +7 495 780 3415 / 3417
Fax: +7 495 780 3418
Email: amelvin@asinex.com / busdev@asinex.com
Web page: http://www.asinex.com